SERUM AMYLOID A (SAA) TEST
2,700 Kshs | Home Collection Available
Synonyms
SAA Test, Serum Amyloid, Inflammation
Purpose
The Serum Amyloid A (SAA) test measures the concentration of serum amyloid A protein in the blood. SAA is an acute-phase reactant that increases rapidly in response to inflammation.
This test is important for detecting and monitoring acute and chronic inflammatory conditions, such as infections, autoimmune diseases, and some cancers. It is also useful in assessing the effectiveness of treatment and the progression or resolution of inflammation.
Other medical laboratory tests commonly performed alongside the SAA test include C-reactive protein (CRP) test, interleukin-6 (IL-6) test, erythrocyte sedimentation rate (ESR), procalcitonin test, and full blood count (FBC).
Patient Preparation
No specific preparation is required for the SAA test.
Samples
1 mL plasma or serum collected in a red-top tube or gel-barrier tube. Separate the Plasma and serum within one hour after sample collection. Samples are stable at room temperature/refrigerated/frozen for 14 days.
Test Method
Chemiluminescence immunoassay (CLIA)
Reference Range
<11.0 mg/L
Results Turnaround
Within 24 hours after sample collection.
Diseases / Diagnostic Indicators
Serum Amyloid A (SAA) levels rise sharply in response to inflammation and tissue injury. Doctors commonly associate elevated SAA levels with acute and chronic infections, autoimmune diseases (such as rheumatoid arthritis and lupus), inflammatory bowel disease, cardiovascular conditions, and certain cancers.
Some possible outcomes of the test include;
High SAA levels
Suggest the presence of active inflammation or an acute-phase response, potentially due to infection, chronic inflammatory conditions, or malignancy. Persistently high levels may also indicate ongoing disease activity or ineffective treatment.
Normal SAA levels
Normal SAA levels show that the body has no significant inflammation or that it has resolved or is now well-managed.
Declining SAA levels
Often reflects successful treatment and a reduction in inflammation. For more information on SAA testing, read this study.