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H. pylori Antigen Test
Synonyms
Campylobacter pylori, Campylobacter from the Stomach, Culture-Helicobacter pylori, H pylori Stool Antigen Test
Purpose of the H. pylori Antigen Test
The H. pylori Antigen Test is a non-invasive stool procedure that detects the presence of Helicobacter pylori antigens, indicating an active infection in the digestive tract.
This bacterium is a common cause of peptic ulcers, gastritis, and other gastrointestinal issues. The test is important for accurately diagnosing H. pylori infections, monitoring treatment effectiveness, and preventing complications like stomach cancer.
Doctors often perform it alongside other tests such as the urea breath test, H. pylori antibody blood test, endoscopy with biopsy, and stool occult blood test to provide a comprehensive assessment of gastrointestinal health.
Patient Preparation
About two weeks before the test, the patient should avoid certain medications, such as antibiotics, antacids, bismuth, proton pump inhibitors (PPIs), and H2 blockers.
Samples for H pylori Stool Antigen
2 g (thumbnail size portion of stool), 2 mL liquid stool. Sterile screw-cap vial. Avoid contaminating the samples and keep them Refrigerated.

Reference Range
IgM- 30 – 40 U/mL, IgG- 0.75 – 1
Results Turnaround
3 days after receipt of samples.
Diseases / Diagnostic Indicators of H. pylori
A positive result means that H. pylori antigens are present in the stool, indicating an ongoing infection. This could lead to conditions like gastritis, duodenal ulcers, or even increase the risk of stomach cancer if left untreated.
A negative result means no H. pylori antigens were found, suggesting that either the infection is not present or has been successfully treated. The test is also useful for checking whether treatment to eliminate the bacteria has worked effectively.
For further information on the effects of H. pylori, see this study on H. pylori-related disorders.