ALK Phosphate Test
500 Kshs | Home Collection Available
Synonyms
Alkaline Phosphate
Purpose
The Alkaline Phosphatase (ALP) test is a blood test that measures the level of the ALP enzyme in your blood. ALP is mainly produced in the liver and bones. This test helps diagnose liver diseases, bile duct blockages, and bone disorders.
Elevated ALP levels may signal liver damage, bone disease, or bile duct obstruction. Identifying the underlying cause is essential for timely and accurate treatment. This test primarily serves for initial diagnosis rather than serial monitoring.
The test can be done alongside Gamma-Glutamyl Transferase (GGT), Liver Function Tests (LFTs), Calcium and Phosphate Levels, Vitamin D Test, and Parathyroid Hormone (PTH).
Patient Preparation
The patient is required to avoid eating or drinking at least 4 hours before the test.
Samples
1ml with a minimum volume of 0.7ml of Serum or plasma collected in a Gel-barrier, red-top, or green-top tube (lithium heparin). Avoid using EDTA, oxalate, or citrate plasma. Separate the plasma or serum from the cells within 45 minutes of sample collection. Transfer separated serum or plasma to a plastic transport tube if red-top or green-top tubes are used. Store the sample at room temperature
Reference Range
Highly dependent on the age and sex of the patient.
Results Turnaround
Within one day of receipt of the sample.
Diseases / Diagnostic indicators
High ALP levels may indicate conditions such as:
- Liver diseases – including hepatitis, cirrhosis, bile duct obstruction, and liver cancer
- Bone disorders – such as Paget’s disease, osteomalacia, bone tumors, or healing fractures
- Gallbladder disease – due to blocked bile ducts
- Pregnancy – mildly elevated ALP is normal due to placental production
Low ALP levels may be seen in:
- Malnutrition
- Zinc or magnesium deficiency
- Hypothyroidism
- Rare genetic disorders affecting bone metabolism
- Elevated ALP suggests liver or bone abnormalities and requires additional tests (like GGT or imaging) to determine the source.
- Normal ALP typically indicates normal liver and bone function.
- Low ALP may point to nutritional deficiencies or underlying metabolic issues and warrants further investigation.
For more on ALK Phosphate Testing, read this study.