Highly Sensitive C-Reactive Protein Test
2,720 Kshs | Home Collection Available
Synonyms
hs-CRP Test
Purpose
The High-Sensitivity C-Reactive Protein (hs-CRP) Test is a blood test that measures low levels of C-reactive protein (CRP), a substance produced by the liver in response to inflammation.
It is particularly useful in detecting chronic low-grade inflammation and is often prescribed to assess the risk of cardiovascular disease or monitor ongoing inflammatory conditions. Doctors may also recommend it for individuals with recurrent bacterial infections or suspected inflammatory disorders.
This test helps identify hidden inflammation in the body, which can be an early indicator of conditions such as heart disease, diabetes, rheumatoid arthritis, or autoimmune diseases. It provides valuable information for evaluating the effectiveness of treatments and determining the need for further medical intervention.
The test can be done alongside Erythrocyte Sedimentation Rate (ESR), Complete Blood Count (CBC), Lipid Profile, Fasting Blood Sugar (FBS), Rheumatoid Factor (RF), Anti-Nuclear Antibody (ANA) Test, and Liver and kidney function tests.
Patient Preparation
The patient’s sex should be stated in the request form.
Samples
1ml plasma or serum collected in a red-top tube or gel-barrier tube. Plasma and serum should be separated within one hour after sample collection. Samples are stable at room temperature for 7 days and refrigerated/frozen for 14 days.
Reference Range
Low risk: <1.00 mg/L
Average risk: 1.00-3.00 mg/L
High risk :> 3.00mg/L
Results Turnaround
Within 24 hours after sample collection.
Diseases / Diagnostic Indicators
Elevated hs-CRP levels indicate the presence of inflammation and may signal an increased risk of developing cardiovascular diseases, such as heart attack or stroke. Levels above 3.0 mg/L are generally considered high and may suggest chronic low-grade inflammation associated with conditions like atherosclerosis, type 2 diabetes, or metabolic syndrome.
Moderate elevations may also appear in autoimmune conditions such as rheumatoid arthritis or lupus, and in chronic infections. Mildly elevated levels (1–3 mg/L) can reflect early inflammation or lifestyle-related factors such as obesity, smoking, or stress.
Normal hs-CRP levels (typically below 1.0 mg/L) suggest a low risk for cardiovascular events and no significant ongoing systemic inflammation.
Basic outcomes of the test:
- High hs-CRP (>3.0 mg/L): High risk of cardiovascular events or active inflammation
- Low hs-CRP (<1.0 mg/L): Low risk of cardiovascular disease
- Moderate hs-CRP (1.0–3.0 mg/L): Moderate risk or mild inflammation
For more on High Sensitive C Reactive Protein Test, read this study.