BIOINFORMATICS TRAINING
NextGen Sequence Analysis
This hands-on training will equip participants with knowledge and skills on how to generate, manipulate, and analyze whole genome, whole exome, and targeted NGS data and discover germline SNPs, indels, SVs, and CNVs; somatic SNVs, SVs, and indels, and RNASeq SNPs and indels. The objective is to enhance the researchers‘ capacity to conduct world class scientific research and boost their institution‘s profile as a leading diagnostic and scientific centre.
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Computer-Aided Drug Design
In this intensive training, partcipants will learn the science involved in disease target identification, virtual screening techniques, in-silico generation of ligands, protein optimization & energy minimization, molecular docking, creation of Grid Paramater & Dock Parameter files, running the Docking Algorithm, pharmacophore modeling, and drug repurposing.
They will also learn how to select potent inhibitors on the basis of binding energies and Lipinski‘s Rule of 5, how to look for H-bonds between ligands and active sites of protein residues as well as aspects of drug Likeness,ADME & Toxicity. Practical hands-on training will encompass training on the use of KenClust, software such as MarvinSketch, UCSF Chimera, AutoDock Tools, Ligand Scout,Open Babel, and SPDV among others. Lab work will include bacterial culture, antimicrobial susceptibility testing, and genotoxicity testing.
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PCR Bootcamp
Polymerase chain reaction (PCR) has been hailed as one of the most important advances in molecular biology and is an indispensable tool in biomedical research. The objective of this intensive 5-day hands-on training is to impart transferrable skills on planning, setting-up, running and analysing PCR experiments.
Participants will be taken through principles of DNA replication, types and variants of PCR, and PCR principles and workflows. They will learn how to design and synthesize primers, prepare samples, design PCR assays, set up software, and apply PCR in DNA cloning for sequencing, functional gene analysis, disease diagnosis, paternity testing, and forensics. PCR Optimization and validation will also be taught. The course is right for any person who has an interest in starting to use PCR or current new users who want further training on Gene Expression Applications.
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