In Silico Vaccine Design | Kenya Institute of Bioinformatics

This 2-day course will cover the state-of-the-art methods for in-silico T- and B cell epitope discovery. We will touch upon different prediction tools and database searches. Publicly available web servers such as The Vaccine Investigation and Online Information Network (VIOLIN; http://www.violinet.org ), Vaccine Page and open-source computational software will be used. A few review papers on prediction servers and methods for epitope identification will be presented.

Aspects of reverse vaccinology including case studies will be presented. No advanced computer skills are needed. Even though we assume a basic knowledge of the major functions of the immune system, important parts will be briefly explained. Training can be done in-house or at a different training location.