Our Stories

On this page, we share insights on themes related to our business and tell stories that reflect our thinking.

Epigenetic Reprogramming, Quiescence, and the Cancer Burden

Epigenomics

" The time has come," the Walrus said, "To talk of many things: Of shoes-and ships-and sealing-wax- Of cabbages-and kings- And why the sea is boiling hot- And whether pigs have wings.", (The Walrus and the Carpenter from Through the Looking Glass-Lewis Carroll)

The time has come to talk of many things. Of cancer, nurture, and genes that are sound but not sound. Of epigenomics and methylones. Of FoxOs, mTOR, and HIFs. Of cancer stem cells, quiescence, and pluripotency. Of pocket handkerchiefs, sobs, tears, and lost hope. Of epigenetic reprogramming, pigs that fly, and the renewal of lost hope...Continue Reading »


Sonic the Hedgehog, Sleeping Beauty and Cancer of the Brain

Sonic the Hedgehog

Sleeping Beauty and Sonic the Hedgehog are among my most favorite childhood heroes. Originally conceived by Charles Perrault, Sleeping Beauty is a story about a beautiful princess called Aurora who got bewitched by a fairy, condemning her into 100 years of sleep. She only wakes up when a handsome prince kisses her. They get married and live happily ever after. A creation of Sega Games, Sonic the Hedgehog is a blue-coloured, anthropormophic character who, together with his sidekick Tails, are in perpetual conflict with Dr. Robotnick. He executes his deadly attacks by curling and forming into a ball. To use clich├ęs, Sonic the Hedgehog takes no prisoners, gives no quarter, and shoots from the hip. It now appears that these 2 characters hold the key in the fight against cancer.Quiet...Continue Reading »


How Bioinformatics will make that Persistent Hacking Cough Shush up

Tuberculosis

Tuberculosis. You have probably heard about Victorian beauties. Of frail little things with lily-white faces and flights of fantasies that became immortalized in verse. Of Snow white with hacking cough, hollow cheeks, thick yellow sputum, night sweats, weakness, and paper weight. Poetic, they called it. They also called it Pthisis and consumption and romanticized these noble suffering souls...Continue Reading »


Silence is Golden, Noise is Cancer

Adenocarcinoma

"LISTEN to me, " said the Demon as he placed his hand upon my head. " The region of which I speak is a dreary region in Libya, by the borders of the river Zaire. And there is no quiet there, nor silence." (From Silence-A Fable by Edgar Allan Poe)

The cell cycle provides a powerful metaphor of silence and speech...Continue Reading »